[Potter]

Originally Posted by Herbal Healer 019

I forgot the origional source but heres 1 that can confirm that this 58mg has been supposedly identified as the LD50 of adderall: http://wiki.answers.com/Q/How_many_a...t_to_be_deadly

An undocumented "wiki-answer" is hardly a valid source.

The fact that you can legally be prescribed 60mg of adderall would be a hell of a good indication that there is something very wrong here.

So a quick google of "LD50 amphetamines leads us to the [url="http://msds.chem.ox.ac.uk/AM/amphetamine_sulfate.html"]MSDS sheet where we see

Toxicity data
(The meaning of any toxicological abbreviations which appear in this section is given here.)
ORL-HMN TDLO 41 mg kg
ORL-RAT LD50 55 mg kg
IPR-RAT LD50 125 mg kg
ORL-MUS LD50 24 mg kg
IVN-MUS LD50 68 mg kg
ORL-DOG LD50 23 mg kg

and from Erowid we get info from the 1998 PDR

Individual patient response to amphetamines varies widely. While toxic symptoms occasionally occur as an idiosyncracy at dosages as low as 2mg, they are rare with doses of less than 15mg; 30mg can produce severe reactions, yet doses of 400 to 500mg are not necessarily fatal. In rats, the oral LD50 of dextroamphetamine sulfate is 96.8 mg/kg.

Now this does not take into account tolerance. In pills-a-go-go by Jim Hogshire, we read

California criminologist Dr. Roger C. Smith who found people mainlining speed in amounts as large as 15,000mg in the course of a day, and he discovered that people could easily withstand intravenous injects of 400 and 500 mg, even if they've never took the drug before

So it looks like the "wiki" missed out on the "per kilogram" part of the equation, though that figure is still rather low when it comes to lethality.


Nobody has been a lifelong user of adderall, generally prefer 30-40mg a day, broken up over the course of a few hours in the morning. Nobody rarely take the stuff much later then 3pm unless they don't plan on sleeping till the wee hours of the morning. If they do desire the effects but want to sleep, they will grind and inhale 5-15mg, though they do not make a habit of this. Nobody can't really stomach more then 60mgs of the stuff at a time.

A friend, used to come and help nobody with some cash in exchange for goods, discovered one day he had a bit of an issue going on. It was probably 10pm, he had to go back to his parents house for the night and leave first thing in the morning for a 6 hour drive to school. He tosses back 80mg of the stuff like it was nothing and remarks how he's off to bed. Turns out he had a pretty severe stimulant habit going and would take what ever he could for upkeep, thankfully he got himself cleaned up and friendship has been maintained.